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Methods Cell culture and transfection HeLa (female, ATCC , CCL-2) and HEK293T (female, ATCC CRL-1573), purchased from ATCC, and OCI-AML2 (male, Leibniz-Institut DSMZ) cells were cultured in Dulbeccos Modified Eagle Medium (DMEM) (ThermoFisher Scientific) supplemented with 10% fetal calf serum (ThermoFisher Scientific), 100 U/ml penicillin, and 100 U/ml streptomycin (ThermoFisher Scientific) at 37 C and 5 % CO 2
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Abstract Introduction The aim of the present analysis was to characterise the absorption, distribution and elimination of semaglutide by means of population pharmacokinetic (PK) models using data from nine clinical pharmacology trials conducted in both healthy subjects and those with type 2 diabetes
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